Emergence of avian H1N1 influenza viruses in pigs in China.
Identifieur interne : 001C02 ( Main/Exploration ); précédent : 001C01; suivant : 001C03Emergence of avian H1N1 influenza viruses in pigs in China.
Auteurs : Y. Guan ; K F Shortridge ; S. Krauss ; P H Li ; Yoshihiro Kawaoka [États-Unis] ; R G WebsterSource :
- Journal of Virology [ 0022-538X ] ; 1996.
Descripteurs français
- KwdFr :
- MESH :
- génétique : Virus de la grippe A.
- virologie : Suidae.
- Animaux, Chine, Embryon de poulet, Génotype, Phylogénie, Sous-type H1N1 du virus de la grippe A, Virus de la grippe A.
- Wicri :
- geographic : République populaire de Chine.
English descriptors
- KwdEn :
- MESH :
- geographic : China.
- classification : Influenza A virus.
- genetics : Influenza A virus.
- virology : Swine.
- Animals, Chick Embryo, Genotype, Influenza A Virus, H1N1 Subtype, Phylogeny.
Abstract
Avian influenza A viruses from Asia are recognized as the source of genes that reassorted with human viral genes to generate the Asian/57 (H2N2) and Hong Kong/68 (H3N2) pandemic strains earlier in this century. Here we report the genetic analysis of avian influenza A H1N1 viruses recently isolated from pigs in southern China, a host suspected to generate new pandemic strains through gene reassortment events. Each of the eight gene segments was of avian origin. Phylogenetic analysis indicates that these genes form an Asian sublineage of the Eurasian avian lineage, suggesting that these viruses are an independent introduction into pigs in Asia. The presence of avian influenza viruses in pigs in China places them in an optimal position for transmission to humans and may serve as an early warning of the emergence of the next human influenza virus pandemic.
Url:
PubMed: 8892928
PubMed Central: 190877
Affiliations:
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Le document en format XML
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<term>Influenza A virus (classification)</term>
<term>Influenza A virus (genetics)</term>
<term>Phylogeny</term>
<term>Swine (virology)</term>
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<term>Chine</term>
<term>Embryon de poulet</term>
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<term>Suidae (virologie)</term>
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<front><div type="abstract" xml:lang="en"><p>Avian influenza A viruses from Asia are recognized as the source of genes that reassorted with human viral genes to generate the Asian/57 (H2N2) and Hong Kong/68 (H3N2) pandemic strains earlier in this century. Here we report the genetic analysis of avian influenza A H1N1 viruses recently isolated from pigs in southern China, a host suspected to generate new pandemic strains through gene reassortment events. Each of the eight gene segments was of avian origin. Phylogenetic analysis indicates that these genes form an Asian sublineage of the Eurasian avian lineage, suggesting that these viruses are an independent introduction into pigs in Asia. The presence of avian influenza viruses in pigs in China places them in an optimal position for transmission to humans and may serve as an early warning of the emergence of the next human influenza virus pandemic.</p>
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<country name="États-Unis"><region name="Wisconsin"><name sortKey="Kawaoka, Y" sort="Kawaoka, Y" uniqKey="Kawaoka Y" first="Y" last="Kawaoka">Yoshihiro Kawaoka</name>
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